Create a new non-NPAPI plugin for Chrome compatibility
The deprecation of NPAPI plugins in Chrome is affecting some functionality in Chrome. We are specifically having issues with the Open in Client Application feature in document libraries. This no longer works in Chrome by default and will no longer work at all in September once it is fully deprecated.
Please create a way for the Open in Client Application (and any other features that are enabled by the NPAPI plugin) to work in Chrome. This true cross-browser support would help improve our user adoption and go a long way towards convincing our users of the benefits of continued usage of SharePoint Online.
we no longer rely on plugins for the “Open in” commands when using the modern document library UX. Instead we use the Office URI schemes (https://docs.microsoft.com/en-us/office/client-developer/office-uri-schemes) for cross-browser and cross-OS compatibility. If you are seeing issues opening Office client apps from Chrome please file a support ticket.